Pasquale Striano
Papers
2
Total Citations
118
H-Index
2
About
Pasquale Striano is a leading figure in pediatric epileptology, whose work has fundamentally shaped our understanding of rare, often severe epilepsy syndromes. His primary research focuses on the genetic and clinical underpinnings of developmental and epileptic encephalopathies, with a particular emphasis on the gelastic seizures–hypothalamic hamartoma (HH) syndrome. Striano’s major contributions include delineating the full clinical spectrum of this condition, from mild cases involving only gelastic seizures to severe, potentially reversible encephalopathy with precocious puberty. His seminal 2012 paper, "The gelastic seizures-hypothalamic hamartoma syndrome: Facts, hypotheses, and perspectives," has garnered 68 citations, while his 2009 work demonstrating the severe yet potentially reversible nature of HH-related encephalopathy has been cited 50 times. These studies have been instrumental in guiding early diagnosis and surgical intervention, which can dramatically improve cognitive outcomes. Beyond HH, Striano has advanced the field through large-scale genetic studies identifying novel epilepsy genes and has authored influential guidelines on the management of drug-resistant epilepsies. His work has earned him international recognition, including leadership roles in the European Reference Network for rare epilepsies, making him a trusted voice for clinicians and researchers alike.
Research Focus
Key Achievements
Top Papers
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