A.S. Martinotti

University of Messina, Radiation Oncology Associates

Papers

Total Citations

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About

A.S. Martinotti is a leading clinical researcher in the field of stereotactic radiosurgery, with a focused expertise in the non-invasive treatment of trigeminal neuralgia (TN). Their work has been instrumental in advancing image-guided robotic radiosurgery, particularly using the CyberKnife system, as a minimally-invasive alternative for patients with medically resistant facial pain. Martinotti’s major contribution lies in demonstrating the safety and efficacy of frameless, non-isocentric irradiation of extended trigeminal nerve segments, a novel approach that has redefined treatment paradigms. Their landmark 2017 study, with 38 citations, introduced this technique, while their 2019 paper, with 35 citations, represents the largest single-center experience to date, reporting clinical outcomes from 387 treatments with three-year follow-up out of a total 560 cases. This extensive dataset has provided critical evidence for the durability and reliability of the procedure. Martinotti’s work has not only expanded the therapeutic arsenal for TN but has also set a new standard for large-scale, long-term outcome reporting in radiosurgery, making them a pivotal figure in the evolution of pain management and neurosurgical oncology.