Oleg A. Andreev
Papers
1
Total Citations
8
H-Index
1
About
Oleg A. Andreev is a leading biophysicist whose research centers on the molecular mechanisms of membrane transport and the development of pH-sensitive targeting technologies for cancer therapy. He is best known for his pioneering work with pH Low Insertion Peptides (pHLIPs), a family of peptides that exploit the acidic microenvironment of tumors to selectively insert into cell membranes and deliver therapeutic or imaging agents directly into cancer cells. His major contributions include demonstrating that pHLIPs can target bladder urothelial carcinoma, as shown in his 2022 study on pHLIP-ICG and pHLIP-amanitin conjugates, which achieved 8 citations. This work highlights the potential of acidity as a universal biomarker for metabolically active tumor cells. Andreev’s research has significantly advanced the field of targeted drug delivery, offering a novel strategy to overcome the limitations of conventional chemotherapy. His findings have implications for both diagnostic imaging and precision oncology, making him a key figure in the development of smart, pH-responsive nanomedicines.
Research Focus
Key Achievements
Top Papers
- 1