Anna Moshnikova
Papers
1
Total Citations
8
H-Index
1
About
Anna Moshnikova is a leading researcher in the targeted delivery of therapeutics and imaging agents, with a primary focus on exploiting tumor acidity as a biomarker. Her key research areas include the development and application of pH Low Insertion Peptides (pHLIPs) for cancer diagnosis and treatment. Moshnikova’s major contributions center on demonstrating that pHLIPs can sense the acidic microenvironment at the surface of tumor cells, enabling the selective intracellular delivery of diverse cargo molecules. In her highly cited 2022 work, she showed the targeting of bladder urothelial carcinoma with pHLIP-ICG for imaging and effectively inhibited urothelial cancer cell proliferation using pHLIP-amanitin, a potent cytotoxic conjugate. This work, which has garnered 8 citations, highlights her impact in advancing precision oncology by turning a universal metabolic feature of tumors into a druggable vulnerability. Her achievements underscore a practical, translatable approach to overcoming the challenges of off-target toxicity in cancer therapy, making her a notable figure in the field of peptide-based drug delivery.
Research Focus
Key Achievements
Top Papers
- 1