Nerea Ruiz
Papers
1
Total Citations
68
H-Index
1
About
Nerea Ruiz is a leading figure in chemical glycobiology, with her research centered on the synthesis and functional study of complex carbohydrates. Her major contribution lies in pioneering chemoenzymatic strategies for constructing N-glycan microarrays, a critical tool for decoding carbohydrate-protein interactions. In her most cited work (68 citations), she reported the first-ever focused microarray of synthetic N-glycans, achieved through a modular chemical synthesis followed by on-chip nanoscale enzymatic glycosylation. This breakthrough allowed for the precise immobilization of diverse N-glycan core structures on glass surfaces, enabling high-throughput screening of glycan-binding proteins. Her work bridges synthetic organic chemistry and enzymology, providing a powerful platform for understanding roles of glycosylation in health and disease. By enabling the systematic study of glycan recognition, Ruiz’s contributions have advanced fields from immunology to cancer biology, establishing her as a key innovator in glycoarray technology.
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