Masayuki Machida
National Institute of Advanced Industrial Science and Technology
Papers
3
Total Citations
18
H-Index
3
About
Masayuki Machida is a researcher specializing in laboratory automation, paramagnetic bead handling, and molecular diagnostics, with a particular focus on developing innovative robotic systems for biological and medical applications. His most recognized contribution is the advancement of Magtration technology, a proprietary approach to automating paramagnetic bead handling that enables efficient separation and resuspension processes. This work culminated in the development of multipurpose robots capable of performing automated cycle sequencing, significantly streamlining genomic workflows. Machida further extended this expertise to the field of genetic analysis, engineering a fully automated SNP typing system using an adapter ligation method combined with paramagnetic bead handling, addressing the growing biological and clinical demand for reliable single nucleotide polymorphism detection. His work also encompasses clinical diagnostics, notably improving the lectin-antibody enzyme immunoassay for alphafetoprotein-L3, a critical tumor marker for liver cancer, enabling its automation for the first time. With citations spanning genomics, automation engineering, and clinical chemistry, Machida's interdisciplinary contributions represent meaningful advances in making complex molecular and diagnostic assays more accessible, reproducible, and efficient for both research and medical communities.
Research Focus
Key Achievements
Top Papers
- 1Multipurpose Robot for Automated Cycle Sequencing9 citations · 2003
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