Mark Ballantyne
Papers
1
Total Citations
41
H-Index
1
About
Mark Ballantyne is a leading figure in genetic toxicology, with a focused expertise in the mutagenic assessment of complex aerosols, particularly mainstream cigarette smoke. His major contribution lies in refining and validating the Ames assay for use with whole smoke exposure systems, moving beyond traditional testing with particulate matter. In his pivotal 2015 work, which has garnered 41 citations, Ballantyne systematically evaluated the suitability of five *Salmonella typhimurium* strains—TA1535, TA1537, TA97, TA102, and TA104—in conjunction with a Vitrocell® VC 10 Smoking Robot and 3R4F reference cigarettes. This research was critical because little data existed on the performance of TA97, TA104, TA1535, TA1537, and TA102 when exposed to a whole aerosol. By demonstrating the utility of these strains, Ballantyne provided the toxicological community with a more comprehensive and physiologically relevant toolkit for assessing the mutagenic potential of inhaled substances, a foundational achievement for regulatory testing and product risk assessment.
Research Focus
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