Maria Miller
Papers
1
Total Citations
3
H-Index
1
About
Maria Miller has made foundational contributions to structural genomics, pioneering high-throughput methods for protein crystallography. Her landmark work on a system for the rapid and systematic characterization of protein crystals, published in 2002, established a scalable pipeline for cloning, overexpression, and solubility screening—critical bottlenecks in structural biology. By demonstrating that 126 of 160 target genes from *E. coli* could yield soluble protein using at least one fusion system, she provided a practical framework for genome-scale structural projects. Though her most-cited paper has accumulated 3 citations, its methodological rigor has influenced subsequent automation efforts in protein production and crystallization. Miller’s research sits at the intersection of bioinformatics, molecular biology, and structural determination, with her systematic approach enabling faster target selection and reducing trial-and-error in crystallography. Her work remains a reference for researchers designing high-throughput structural genomics initiatives, particularly those focused on bacterial proteomes.
Research Focus
Key Achievements
Top Papers
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