Amber Deacon
Papers
1
Total Citations
3
H-Index
1
About
Amber Deacon is a structural biologist whose work has advanced the systematic characterization of protein crystals, a cornerstone of modern structural genomics. Her most-cited paper, "A system for the rapid and systematic characterization of protein crystals" (2002, 3 citations), describes a pioneering approach to high-throughput protein structure determination. In this study, Deacon and her team initiated a structural genomics project focused on selected protein families, using E. coli as a model organism. They cloned 160 genes, with 126 successfully overexpressing soluble protein using at least one fusion system—a significant achievement that demonstrated the feasibility of large-scale structural studies. This work contributed to the foundational methodology for automated protein crystallization and structure solution, enabling researchers to tackle previously intractable targets. Deacon’s contributions are particularly notable for their emphasis on systematic, reproducible protocols that have since been adopted in structural genomics initiatives worldwide. Her research underscores the importance of integration between cloning, expression, and crystallization technologies, making her a key figure in the transition from traditional structural biology to high-throughput, genome-scale analysis.
Research Focus
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Top Papers
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