Marcel Scheideler
Papers
1
Total Citations
131
H-Index
1
About
Marcel Scheideler is a pioneering researcher in functional genomics and systems biology, best known for his foundational work in high-throughput transcriptomics. His major contributions center on developing large-scale genomic tools to map gene expression, most notably through the comprehensive transcriptional profiling of all open reading frames (ORFs) in *Saccharomyces cerevisiae*. In his landmark 1998 study, which has garnered 131 citations, Scheideler and his team PCR-amplified 6,116 yeast ORFs using over 12,000 custom primers, achieving a remarkable 97% success rate. They then arrayed these products at ultra-high density, enabling systematic hybridization studies that revolutionized yeast functional genomics. This work provided a critical resource for the budding yeast community, facilitating global analyses of gene regulation and cellular pathways. Scheideler’s achievements exemplify the power of combining meticulous experimental design with scalable molecular techniques, laying the groundwork for modern transcriptome-wide studies. His research continues to influence fields from metabolic engineering to biomedical discovery, underscoring his lasting impact on genomic science.
Research Focus
Key Achievements
Top Papers
- 1Transcriptional profiling on all open reading frames ofSaccharomyces cerevisiae131 citations · 1998