Debashish Roy

Papers

Total Citations

101

H-Index

About

Debashish Roy is a pioneer in high-resolution whole-body imaging, with his work fundamentally advancing how researchers visualize biological processes at the cellular level within intact organisms. His primary research focuses on cryo-imaging technology, specifically the development of the Case Cryo-imaging system—a revolutionary technique that combines a motorized cryo-microtome with advanced fluorescence and brightfield microscopy. Roy’s major contribution is enabling single-cell detection of fluorescently labeled cells in whole mice, a breakthrough with profound implications for tracking stem cells and metastatic cancer cells in vivo. His seminal 2009 paper, "3D Cryo‐Imaging: A Very High‐Resolution View of the Whole Mouse," has garnered 86 citations, establishing the foundation for this field. A subsequent study, "Cryo-imaging of fluorescently labeled single cells in a mouse," further demonstrated the system’s unparalleled resolution, earning 15 citations. By providing information-rich, 3D molecular fluorescence images without tissue disruption, Roy’s work bridges the gap between macroscopic imaging and microscopic histology, offering researchers an indispensable tool for preclinical studies. His innovations continue to shape the future of biomedical imaging and cell tracking.