Bertrand Tavitian
Papers
3
Total Citations
137
H-Index
3
About
Bertrand Tavitian is a leading figure in molecular imaging, whose work has fundamentally advanced the use of positron emission tomography (PET) for neuroinflammation. His primary research focus is the development of novel radiotracers targeting the translocator protein (TSPO, 18 kDa), a key biomarker of activated microglia in the brain. Tavitian’s major contribution lies in the radiosynthesis of several critical TSPO ligands, including [¹⁸F]DPA-714, [¹⁸F]PBR111, and [¹⁸F]PBR28. These compounds have become indispensable tools for visualizing neuroinflammatory processes in conditions such as Alzheimer’s disease, multiple sclerosis, and stroke, enabling researchers to track disease progression and evaluate therapeutic interventions in vivo. His seminal 2008 paper on the radiosynthesis of [¹⁸F]DPA-714 has garnered 88 citations, underscoring its foundational impact. By engineering these high-affinity, selective radioligands and establishing automated, reproducible synthesis protocols, Tavitian has bridged the gap between radiochemistry and clinical application, empowering a global community of neuroscientists to probe the dynamic role of neuroinflammation in brain health and disease.
Research Focus
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Top Papers
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