Bente Risberg
Papers
1
Total Citations
109
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1
About
Bente Risberg is a leading researcher in the field of liquid biopsy and circulating tumor DNA (ctDNA), with a primary focus on the pre-analytical variables that govern the reliability of noninvasive cancer diagnostics. Her work has been instrumental in establishing rigorous protocols for the collection, processing, and storage of blood samples, directly addressing the critical challenge of distinguishing tumor-derived DNA from background cell-free DNA (cfDNA) released by normal cells. Risberg’s most influential study, with 109 citations, systematically demonstrates how common pre-analytical procedures can artificially elevate cfDNA levels due to leukocyte lysis, thereby compromising the sensitivity and specificity of ctDNA detection. This foundational contribution has shaped best practices across the field, ensuring that subsequent clinical applications—from early cancer detection to treatment monitoring—are built on a robust methodological framework. Her research is essential reading for any scientist or clinician working with liquid biopsies, as it underscores that the quality of a result begins long before the assay itself.
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