Christine Parkinson
Papers
1
Total Citations
109
H-Index
1
About
Dr. Christine Parkinson is a leading translational researcher whose work focuses on the pre-analytical variables that underpin the reliability of liquid biopsy in oncology. Her primary research areas include circulating tumor DNA (ctDNA) analysis, cell-free DNA (cfDNA) biology, and the standardization of blood collection protocols for noninvasive cancer management. Dr. Parkinson’s most impactful contribution is her landmark 2018 study, “Effects of Collection and Processing Procedures on Plasma Circulating Cell-Free DNA from Cancer Patients,” which has garnered 109 citations. This work systematically demonstrated how common pre-analytical factors—such as tube type, processing time, and centrifugation—can dramatically alter cfDNA levels through leukocyte lysis, thereby confounding ctDNA detection. By identifying these critical variables, she provided the evidence base for standardized protocols that are now essential for reproducible liquid biopsy research and clinical implementation. Her findings have directly influenced best practices in circulating nucleic acid analysis, helping to ensure that the minute fraction of tumor-derived DNA in plasma can be reliably distinguished from background genomic DNA. Dr. Parkinson’s rigorous approach to pre-analytical quality control continues to shape the field, making her a vital figure in the quest for robust, noninvasive cancer diagnostics.
Research Focus
Key Achievements
Top Papers
- 1