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About

Carlos Caldas is a leading figure in translational cancer research, whose work has fundamentally reshaped how we detect and monitor malignancies through liquid biopsy. His primary research areas center on circulating tumor DNA (ctDNA) and the pre-analytical variables that govern its reliable detection in plasma. Dr. Caldas’s major contribution lies in systematically identifying how blood collection and processing procedures directly impact the integrity and yield of cell-free DNA (cfDNA), a critical step for enabling noninvasive cancer management. His landmark 2018 study on this topic has garnered over 109 citations, serving as a foundational reference for laboratories worldwide seeking to minimize artifacts from leukocyte lysis. Beyond oncology, Dr. Caldas has demonstrated remarkable interdisciplinary breadth, pioneering data-fusion approaches in construction engineering—a field where combining heterogeneous data sources enhances measurement reliability and reduces ambiguity. This dual expertise underscores his versatility as a researcher who applies rigorous analytical frameworks across vastly different domains. Dr. Caldas’s work continues to empower clinicians and scientists to harness the full potential of liquid biopsies, ensuring that the promise of personalized oncology is built on a robust, reproducible foundation.