Optical driven master-slave controllable nano-manipulator with real-time force sensing

Abstract

We have been developing optical driven nano machine to establish innovative research tool for micro biology. Remote manipulation of single cell in liquid with simultaneous reaction force sensing was realized using optically trapped multi-degrees of freedom nano-robots. "Nano-mover" was specially designed and fabricated for cell compression, and the reaction force was calculated simultaneously using video image analysis. Real time elasticity measurement of living cell in liquid was successfully demonstrated for the first time.