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Cytoskeletal motor-driven active self-assembly in in vitro systems

Amy T. Lam, Virginia VanDelinder, Arif Md. Rashedul Kabir, Henry Hess, George D. Bachand, Akira Kakugo

发表年份
2015
引用次数
49

摘要

Molecular motor-driven self-assembly has been an active area of soft matter research for the past decade. Because molecular motors transform chemical energy into mechanical work, systems which employ molecular motors to drive self-assembly processes are able to overcome kinetic and thermodynamic limits on assembly time, size, complexity, and structure. Here, we review the progress in elucidating and demonstrating the rules and capabilities of motor-driven active self-assembly. We focus on the types of structures created and the degree of control realized over these structures, and discuss the next steps necessary to achieve the full potential of this assembly mode which complements robotic manipulation and passive self-assembly.

关键词

CytoskeletonIn vitroCell biologyMotor proteinChemistryBiophysicsNanotechnologyBiologyMaterials scienceMicrotubule

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