Polymerase

Bridge helix and trigger loop perturbations generate superactive RNA polymerases

Lin Tan, Simone C. Wiesler, Dominika Trzaska, Hannah C. Carney, Robert O. J. Weinzierl

Citations: 92 • 2008

Protein quantification from complex protein mixtures using a proteomics methodology with single-cell resolution

Hongtao Zhang, Janet Estee Kacharmina, Kevin Miyashiro, Mark I. Greene, James Eberwine

Citations: 83 • 2001

Ultrasensitive magnetic DNAzyme-copper nanoclusters fluorescent biosensor with triple amplification for the visual detection of E. coli O157:H7

Ziqi Zhou, Yangzi Zhang, Mingzhang Guo, Kunlun Huang, Wentao Xu

Citations: 82 • 2020

Single‐Molecule Studies on DNA and RNA

Karl Otto Greulich

Citations: 34 • 2005

An improved nonisotopic test to screen a large series of new inhibitor molecules of poly(ADP-ribose) polymerase activity for therapeutic applications.

Patrice Decker, Everson Alves Miranda, Gilbert de Murcia, Sylviane Muller

Citations: 30 • 1999

High Throughput RNA Extraction and PCR Inhibitor Removal of Settled Solids for Wastewater Surveillance of SARS-CoV-2 RNA v1

Aaron Topol

Citations: 29 • 2021

The Bridge Helix of RNA Polymerase Acts as a Central Nanomechanical Switchboard for Coordinating Catalysis and Substrate Movement

Robert O. J. Weinzierl

Citations: 27 • 2011

The RNA polymerase factory: a robotic in vitro assembly platform for high-throughput production of recombinant protein complexes

Sven Nottebaum, Lin Tan, Dominika Trzaska, Hannah C. Carney, Robert O. J. Weinzierl

Citations: 25 • 2007

Multiplex Detection of Hotspot Mutations by Rolling Circle-Enabled Universal Microarrays

Daniela P. Ladner, John H. Leamon, Stefan Hamann, Gemma Tarafa, Todd Strugnell, Deborah Dillon, Paul M. Lizardi, José Costa

Citations: 25 • 2001

Microsatellites and the new genetic maps

P.N. Goodfellow

Citations: 12 • 1993

Nanomechanical constraints acting on the catalytic site of cellular RNA polymerases

Robert O. J. Weinzierl

Citations: 11 • 2010

Efficient DNA sequencing on microtiter plates using dried reagents and Bst DNA polymerase

James J. Earley, Helena Kuivaniemi, Darwin J. Prockop, Gerard Tromp

Citations: 9 • 1993

HTS discovery of PARP1-HPF1 complex inhibitors in cancer

Timothy Kellett, Rida Noor, Qiong Zhou, Hector Esquer, Rita Sala, Petra Stojanovic, Johannes Rudolph, Karolin Luger, Daniel V. LaBarbera

Citations: 7 • 2023

Dataset of high-throughput ligand screening against the RNA Packaging Signals regulating Hepatitis B Virus nucleocapsid formation

Fardokht A. Abulwerdi, Farzad Fatehi, Iain W. Manfield, Stuart F.J. Le Grice, John S. Schneekloth, Reidun Twarock, Peter G. Stockley, Nikesh Patel

Citations: 3 • 2022

High-throughput Kinetics using capillary Electrophoresis and Robotics (HiKER) platform used to study T7, T3, and Sp6 RNA polymerase misincorporation

Zachariah I. Carter, William O’Brien, Sean Lund, Andrew F. Gardner

Citations: 3 • 2024

Integrity and Amplification of Nucleic Acids From Snap-Frozen Prostate Tissues From Robotic-Assisted Laparoscopic and Open Prostatectomies

Barbara L. Voss, Kristine Santiano, Mary Milano, Kathy A. Mangold, Karen L. Kaul

Citations: 2 • 2013

A simple cell-based high throughput screening (HTS) assay for inhibitors of Salmonella enterica RNA polymerase containing the general stress response regulator RpoS (σS)

Javier Campos, Jorge A. Benítez

Citations: 2 • 2018