Zhengxing Ge
Papers
1
Total Citations
6
H-Index
1
About
Zhengxing Ge is a medicinal chemist and molecular imaging scientist whose research centers on the development of novel positron emission tomography (PET) radiotracers for imaging neuroinflammation and cancer. His most cited work focuses on the automated synthesis and evaluation of a spiroquinazolinone-based radioligand targeting inducible nitric oxide synthase (iNOS), a key biomarker of microglial activation in neuroinflammatory conditions. This study, which has garnered 6 citations, demonstrates Ge’s expertise in radiochemistry and his strategic approach to designing PET/MR imaging agents that can noninvasively visualize iNOS expression in the brain. By carefully defining a synthetic route and conducting initial biological evaluations, Ge has laid critical groundwork for translating iNOS-targeted imaging into preclinical and clinical applications. His contributions are particularly significant for advancing the understanding of neuroinflammation in diseases such as Alzheimer’s, multiple sclerosis, and stroke. Ge’s work exemplifies the integration of organic synthesis, radiochemistry, and molecular imaging, offering a powerful tool for both basic neuroscience research and diagnostic development. His achievements highlight his role in pushing the boundaries of targeted molecular imaging.
Research Focus
Key Achievements
Top Papers
- 1