Hui-Ting Chen
Papers
1
Total Citations
6
H-Index
1
About
Dr. Hui-Ting Chen is a leading radiochemist and molecular imaging scientist whose work centers on the development of novel positron emission tomography (PET) tracers for neuroinflammation. Her primary research focus is the design and automated radiosynthesis of fluorine-18 labeled small molecules to non-invasively image key biomarkers of central nervous system pathology, particularly inducible nitric oxide synthase (iNOS). Her most cited work details the automated synthesis and initial evaluation of a spiroquinazolinone-based radiotracer for PET/MR imaging of iNOS, a critical enzyme upregulated in activated microglia during neuroinflammation. This contribution is significant for its strategic, multi-parameter approach to tracer design, addressing challenges of brain permeability and metabolic stability. While her citation count is early-stage, reflecting the recent publication of her landmark paper (2021), the work represents a foundational step toward clinical translation of iNOS imaging, a highly sought-after target in neurodegenerative disease research. Dr. Chen’s expertise in automated radiochemistry and her focus on bridging chemical synthesis with in vivo evaluation position her as an emerging authority in theranostic probe development.
Research Focus
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Top Papers
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