Zheng Lin Tan
Papers
1
Total Citations
53
H-Index
1
About
Zheng Lin Tan is a pioneering researcher in synthetic biology and protein engineering, with a focus on high-throughput screening technologies for industrial enzyme production. His most impactful work centers on the development of innovative microfluidic platforms for directed evolution, particularly in the yeast *Pichia pastoris*. Tan's landmark 2019 study, "Gel microdroplet–based high-throughput screening for directed evolution of xylanase-producing Pichia pastoris," has garnered 53 citations and introduced a transformative method for rapidly evolving xylanase—a critical enzyme for biofuel and paper industries. By encapsulating single cells in gel microdroplets, his approach dramatically accelerates the identification of superior enzyme variants, reducing screening time from weeks to hours. This work not only advances the fundamental understanding of directed evolution but also provides a scalable, cost-effective tool for industrial biotechnology. Tan's contributions have been recognized for bridging the gap between microfluidics and applied enzymology, offering a blueprint for engineering other industrially relevant enzymes. His research continues to inspire new strategies in protein engineering, making him a key figure in the quest for sustainable bioprocessing solutions.
Research Focus
Key Achievements
Top Papers
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