Xin‐Hui Xing
Papers
1
Total Citations
53
H-Index
1
About
Xin-Hui Xing is a leading figure in synthetic biology and metabolic engineering, with a focus on developing high-throughput screening platforms for directed evolution of industrial enzymes and microbial cell factories. Her most-cited work, published in 2019, introduced a gel microdroplet–based high-throughput screening method for directed evolution of xylanase-producing *Pichia pastoris*, a breakthrough that has garnered 53 citations and enabled rapid, cost-effective selection of enzyme variants with enhanced activity. This contribution addresses a critical bottleneck in protein engineering by replacing labor-intensive, low-throughput screening with a microfluidic approach that encapsulates single cells in gel droplets, allowing for precise quantification of enzyme secretion. Xing’s research integrates microfluidics, synthetic biology, and bioprocess engineering to accelerate the development of biocatalysts for lignocellulosic biomass conversion, with implications for sustainable biofuel and biochemical production. Her work has been recognized for its innovation in merging droplet-based systems with directed evolution, offering a scalable platform for industrial biotechnology. Through these efforts, Xing has established herself as a key innovator in high-throughput screening technologies, bridging the gap between laboratory evolution and industrial application.
Research Focus
Key Achievements
Top Papers
- 1