Yvette Seppenwoolde
Papers
3
Total Citations
333
H-Index
3
About
Yvette Seppenwoolde is a leading expert in the field of radiation oncology, specializing in the management of respiratory-induced tumor motion. Her pioneering work has been instrumental in advancing the clinical application of the CyberKnife robotic radiosurgery system, particularly through her research on the Synchrony Respiratory Tracking System (RTS). Seppenwoolde’s major contributions include the first rigorous simulation and experimental validation of this technology, demonstrating its ability to accurately compensate for moving lung tumors. Her landmark 2007 simulation study, with over 260 citations, established the fundamental accuracy of the Synchrony algorithm, while her subsequent 2008 experimental study provided critical dosimetric evidence of its clinical viability. More recently, she has addressed a key limitation of the technology by developing a novel approach to correct for baseline drifts in respiratory motion, further enhancing treatment precision. With a total of over 330 citations across her most-cited works, Seppenwoolde’s research has directly shaped the safe and effective delivery of stereotactic body radiotherapy (SBRT) for lung cancer patients, allowing for normal breathing during treatment without compromising dose delivery.
Research Focus
Key Achievements
Top Papers
- 1
- 2
- 3