Yanan Che

Xiamen University, Chinese University of Hong Kong

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About

Yanan Che is a pioneering researcher at the intersection of microalgae engineering and biomedical micro-robotics. Their work focuses on developing biohybrid microswimmers—living organisms integrated with synthetic materials—for targeted therapeutic and imaging applications. Che’s most-cited study, “Multifunctional Spirulina-hybrid helical microswimmers: Imaging and photothermal efficacy enabled by intracellular gold deposition” (2024, 16 citations), demonstrates a breakthrough: using Spirulina microalgae as natural helical scaffolds, they achieved intracellular gold nanoparticle deposition, enabling both fluorescence imaging and photothermal therapy. This work showcases how biohybrid designs can combine biological motility with synthetic functionality. A subsequent paper, “Engineering microalgae-based biohybrid robots for biomedical applications” (2025, 9 citations), further establishes Che’s leadership in this emerging field, outlining design principles for algae-based robots that are biocompatible, steerable, and multifunctional. Che’s contributions are notable for their creativity in repurposing photosynthetic organisms into active, controllable therapeutic agents. Their research holds promise for non-invasive cancer treatment and targeted drug delivery, positioning Che as a rising innovator in biohybrid robotics and nanomedicine.