Xiaowen He

Shanghai Cell Therapy Research Institute

Papers

Total Citations

H-Index

About

Xiaowen He is a biomedical researcher specializing in cryopreservation and regenerative medicine, with a focus on optimizing the storage and viability of therapeutic cells. Her most cited work, "Optimization of UC-MSCs cold-chain storage by minimizing temperature fluctuations using an automatic cryopreservation system" (2020), has garnered 19 citations, highlighting its significance in addressing a critical bottleneck in cell therapy—maintaining umbilical cord-derived mesenchymal stem cell (UC-MSC) integrity during transport and storage. He’s major contribution lies in demonstrating that automated, temperature-stable cryopreservation systems can dramatically reduce cellular damage from thermal fluctuations, improving post-thaw viability and functional recovery of MSCs. This work has practical implications for scaling cell-based therapies, ensuring that patients receive high-quality treatments regardless of geographic distance. By tackling cold-chain logistics, He bridges engineering and biology, offering a reproducible solution for clinical translation. Her research is particularly valuable for students and researchers in biobanking, tissue engineering, and translational medicine, as it underscores the importance of environmental control in preserving stem cell potency. He’s findings pave the way for more reliable, cost-effective cell therapy delivery systems.