Todd G. Mainprize
Papers
2
Total Citations
64
H-Index
2
About
Todd G. Mainprize is a leading figure in the field of stereotactic radiosurgery (SRS) and radiation oncology, with a focused expertise in optimizing head immobilization and treatment delivery for brain tumors. His research addresses a critical clinical question: how to balance patient comfort with the extreme precision required for linac-based SRS. His most cited work, a 2018 cone-beam CT analysis of frameless head immobilization devices (62 citations), provides a rigorous, evidence-based comparison of their reproducibility and ability to limit intrafractional motion. This study directly informs clinical safety protocols, helping practitioners decide whether to use a frame or a frameless system for individual patients. Mainprize has also contributed to the literature on hypofractionated stereotactic radiation therapy (hfSRT), evaluating outcomes for both intact brain metastases and postoperative surgical cavities. His work is instrumental for clinicians seeking to deliver high-dose radiation with millimeter accuracy, ultimately improving the therapeutic ratio for patients with intracranial disease.
Research Focus
Key Achievements
Top Papers
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