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About

Thomas Stefan Worst is a urologic surgeon and clinical researcher whose work centers on advancing surgical techniques for prostate and kidney cancers, with a particular emphasis on robotic-assisted procedures and perioperative optimization. His most impactful contributions address two critical challenges in urologic oncology: managing complications after radical prostatectomy and refining salvage therapies for recurrent disease. Worst led the PELYCAN trial, a randomized phase 3 study demonstrating that a peritoneal flap significantly reduces symptomatic lymphocele formation following robotic-assisted radical prostatectomy with lymph node dissection—a finding with direct implications for postoperative recovery. His work on salvage robotic-assisted laparoscopic radical prostatectomy after focal HIFU therapy, cited 17 times, provides crucial feasibility data for men with recurrent ISUP 2/3 prostate cancer. More recently, Worst has pioneered a kidney-adjusted ERAS protocol for partial nephrectomy, aiming to optimize fluid management and blood pressure control to improve nephron-sparing outcomes. With over 48 citations across his most-cited papers, his research is shaping evidence-based surgical practice in urologic oncology.