Stef van Lieshout

Papers

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About

Stef van Lieshout is a leading figure in the field of cancer genomics, with a primary focus on translating advanced sequencing technologies into clinical diagnostics. His most impactful work centers on the clinical validation of whole genome sequencing (WGS) for cancer care, demonstrating that WGS using fresh-frozen tissue and matched blood samples can serve as a comprehensive, all-inclusive genetic tumor test. This landmark study, which has garnered 86 citations, addresses a critical need in oncology: the ability to screen multiple biomarkers from increasingly small biopsy samples. By advocating for a single, complete test over a patchwork of assays, van Lieshout’s research directly improves diagnostic efficiency and precision. His contributions are pivotal in moving WGS from research labs into routine clinical practice, promising more personalized treatment strategies for patients. Through this work, van Lieshout has established himself as a key innovator at the intersection of genomics and clinical oncology, shaping the future of cancer diagnostics.