Bauke Ylstra

Papers

Total Citations

H-Index

About

Bauke Ylstra is a leading figure in cancer genomics, whose work has fundamentally advanced how we profile tumors at the molecular level. His research centers on the clinical application of whole genome sequencing (WGS) and the detection of copy number alterations, with a particular focus on translating these technologies from the lab bench to the patient bedside. Ylstra’s most notable contribution is his pioneering work in clinically validating WGS for cancer diagnostics, demonstrating that a single, all-inclusive test using fresh-frozen tissue and matched blood samples can replace multiple, fragmented biomarker assays—a paradigm shift for precision oncology. This landmark study, published in 2021, has already garnered 86 citations, underscoring its immediate impact on the field. By championing the use of WGS on even small biopsy samples, Ylstra is helping to solve a critical bottleneck in modern cancer care: the need for comprehensive genomic profiling from limited tissue. His work not only improves diagnostic accuracy but also paves the way for more efficient, cost-effective tumor testing, making him a key architect of the future of molecular pathology.