Shih-Huang Chang
Papers
1
Total Citations
62
H-Index
1
About
Shih-Huang Chang is a leading figure in chemical biology and glycomics, renowned for pioneering surface chemistry techniques that enable high-throughput studies of carbohydrate interactions. His most impactful work introduced a novel glycan array platform using aluminum oxide-coated glass slides, where glycans are immobilized through phosphonate chemistry or noncovalent polyfluorinated hydrocarbon tails. This innovation, detailed in his 2010 paper (62 citations), revolutionized the analysis of enzymatic reactions and protein-glycan binding, providing a robust, reproducible tool for deciphering the biological roles of carbohydrates. Chang’s contributions have significantly advanced the field of glycan microarrays, facilitating discoveries in cell signaling, pathogen recognition, and drug development. His research bridges materials science and biochemistry, demonstrating how tailored surface chemistries can solve complex biological problems. With a citation record reflecting the foundational nature of his work, Chang continues to influence researchers exploring the “sugar code” of cellular communication. His achievements underscore the power of interdisciplinary approaches in creating transformative technologies for biomedical research.
Research Focus
Key Achievements
Top Papers
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