Papers
1
Total Citations
62
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1
About
Chung-Yi Wu is a leading figure in chemical biology, whose work has fundamentally advanced the study of carbohydrates and their biological roles. His primary research focuses on the development of innovative glycan arrays and chemical tools for glycobiology. Wu’s most impactful contribution is the creation of a novel glycan array on aluminum oxide-coated glass slides using phosphonate chemistry, a method that allows for both covalent and noncovalent attachment of glycans. This technology, detailed in his highly cited 2010 paper (62 citations), enables the high-throughput analysis of enzymatic reactions and protein-carbohydrate interactions, providing a powerful platform for understanding cell-surface recognition. By employing a polyfluorinated hydrocarbon tail for noncovalent immobilization, Wu’s approach offers a stable and versatile system for probing the complex language of glycans. His work has been instrumental in making glycan array technology more accessible and robust, directly impacting fields from immunology to drug discovery. Wu’s achievements have established him as a key innovator in chemical glycobiology, providing essential tools for researchers worldwide.
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