Jeng‐Liang Han
Papers
1
Total Citations
62
H-Index
1
About
Jeng‐Liang Han is a leading figure in chemical biology and glycochemistry, renowned for pioneering innovations in glycan array technology. His most cited work, "Glycan Array on Aluminum Oxide-Coated Glass Slides through Phosphonate Chemistry" (2010, 62 citations), introduced a groundbreaking platform that leverages phosphonate chemistry to immobilize glycans—both covalently and noncovalently—on aluminum oxide-coated glass slides. This method, which utilizes glycans tagged with a polyfluorinated hydrocarbon tail, enables high-throughput screening of enzymatic reactions and protein-carbohydrate interactions with exceptional stability and sensitivity. Han’s contributions have significantly advanced the study of glycan-binding proteins, offering a robust tool for deciphering complex biological recognition events. With over 60 citations on this seminal paper alone, his work has influenced fields ranging from immunology to drug discovery. By simplifying the fabrication of glycan arrays, Han has empowered researchers to explore carbohydrate-mediated processes with unprecedented precision, cementing his reputation as an innovator in biointerface design and a key enabler of glycobiology research.
Research Focus
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Top Papers
- 1