Sharon Cooley

Rotunda Hospital

Papers

1

Total Citations

124

H-Index

1

About

Sharon Cooley is a leading researcher in maternal-fetal medicine, with a primary focus on the genetic underpinnings of pregnancy-related liver disorders, particularly intrahepatic cholestasis of pregnancy (ICP). Her major contributions center on unraveling the complex genetic architecture of ICP, demonstrating that the condition arises from a combination of rare mutations and common susceptibility variants in canalicular transporter genes. Her landmark 2013 study, cited over 120 times, provided a comprehensive analysis of genetic variation around six candidate loci, significantly advancing the understanding of how heterozygous mutations and population alleles like ABCB11 p.444A contribute to disease risk. Cooley’s work has been instrumental in bridging the gap between basic genetic discovery and clinical risk assessment, offering insights that help identify at-risk pregnancies and guide management strategies. Her research is widely recognized for its depth and translational impact, making her a key figure in the field of obstetric genetics and a valuable resource for students and clinicians seeking to understand the genetic determinants of pregnancy complications.

Research Focus

Key Achievements

1
H-Index
1
Papers
124
Total Citations
124
Avg Citations/Paper
🏆 Most Cited Paper
A Comprehensive Analysis of Common Genetic Variation Around Six Candidate Loci for Intrahepatic Cholestasis of Pregnancy
124 citations · 2013
📈 Most Prolific Year: 2013 (1 Papers)
🤝 Key Collaborators: 22
🏛 Institutions: Rotunda Hospital

Top Papers

  1. 1

Key Collaborators

Contact & Links

Available for collaboration
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