Ronald van Eijk
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1
Total Citations
35
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About
Ronald van Eijk is a molecular biologist whose research focuses on the detection and analysis of somatic mutations in cancer, with a particular emphasis on KRAS mutations and their implications for personalized oncology. His most-cited work, "Sensitive and Specific KRAS Somatic Mutation Analysis on Whole-Genome Amplified DNA from Archival Tissues" (2009, 35 citations), introduced a robust method for identifying KRAS mutations in formalin-fixed, paraffin-embedded (FFPE) tissues—a critical advance for clinical diagnostics. By combining whole-genome amplification with highly sensitive mutation detection, van Eijk enabled reliable analysis of limited or degraded archival samples, directly impacting the selection of patients for targeted therapies in colorectal and lung cancers. His contributions have been instrumental in bridging the gap between research-grade molecular techniques and routine clinical practice, ensuring that even small biopsy specimens can yield actionable genetic information. Van Eijk’s work underscores the importance of methodological rigor in translational oncology, and his approach remains a benchmark for mutation analysis in archived tissues, supporting both retrospective studies and prospective patient care.
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