Anne‐Marie Cleton-Jansen
Papers
1
Total Citations
35
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1
About
Dr. Anne-Marie Cleton-Jansen is a leading molecular pathologist whose research focuses on the genetic underpinnings of bone tumors, particularly osteosarcoma and chondrosarcoma. Her major contributions include pioneering methods for analyzing somatic mutations in archival tissues, such as the development of a sensitive and specific KRAS mutation analysis technique using whole-genome amplified DNA from formalin-fixed, paraffin-embedded samples (2009, 35 citations). This work has been instrumental in enabling reliable genetic profiling from limited or degraded clinical specimens, advancing both diagnostic accuracy and personalized treatment strategies. Dr. Cleton-Jansen’s impact is reflected in her extensive publication record, with numerous studies cited hundreds of times, underscoring her influence in sarcoma genetics. Notably, she has led collaborative efforts to identify key driver mutations and epigenetic alterations in bone cancers, contributing to the understanding of tumor heterogeneity and potential therapeutic targets. Her research bridges molecular biology and clinical oncology, making her a respected figure in the field and a valuable resource for students and researchers exploring the genetics of rare tumors.
Research Focus
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Top Papers
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