Regina Burton
Papers
1
Total Citations
108
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1
About
Dr. Regina Burton has made foundational contributions to bioanalytical chemistry, particularly in the development of high-throughput sample preparation techniques for liquid chromatography-tandem mass spectrometry (LC/MS/MS). Her landmark 1998 paper, which has garnered over 108 citations, introduced the innovative use of 96-well disk solid phase extraction (SPE) plates operated by robotic systems. This work revolutionized the rapid analysis of drugs and their metabolites in biological matrices by enabling the simultaneous extraction of 96 samples, dramatically increasing throughput while maintaining analytical precision. The disk-based sorbent design she championed improved extraction efficiency and reproducibility, setting a new standard for bioanalysis in pharmaceutical development and clinical research. Dr. Burton’s contributions have been instrumental in accelerating drug discovery and pharmacokinetic studies, reducing sample preparation time from hours to minutes. Her work remains a cornerstone reference for researchers seeking robust, scalable methods for high-throughput bioanalysis, and her innovations continue to influence modern laboratory automation and mass spectrometry workflows.
Research Focus
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