Deborah Buhrman
Papers
1
Total Citations
108
H-Index
1
About
Deborah Buhrman has made foundational contributions to bioanalytical chemistry, particularly in the development of high-throughput sample preparation techniques for liquid chromatography–mass spectrometry (LC/MS). Her landmark 1998 work introduced the use of a 96-well disk solid phase extraction (SPE) plate operated by robotic automation, enabling the simultaneous extraction of drugs and metabolites from biological matrices. This innovation dramatically accelerated bioanalysis, reducing sample preparation time while improving reproducibility and sensitivity. With over 100 citations, this method became a standard in pharmaceutical and clinical laboratories, facilitating faster drug discovery and pharmacokinetic studies. Buhrman’s work bridged the gap between manual, low-throughput workflows and modern, automated bioanalysis, directly impacting how researchers process complex biological samples. Her contributions remain essential for high-speed LC/MS/MS bioanalysis, underscoring her role in advancing analytical efficiency and throughput in drug development.
Research Focus
Key Achievements
Top Papers
- 1