Peter Roepstorff

Papers

Total Citations

152

H-Index

About

Peter Roepstorff is a pioneering figure in mass spectrometry-based proteomics, with a career spanning over four decades. His key research areas include protein chemistry, post-translational modifications, and the development of analytical methods for biological mass spectrometry. Roepstorff is best known for his foundational work on matrix-assisted laser desorption/ionization (MALDI) mass spectrometry, where he contributed to the technique's application for protein and peptide analysis, revolutionizing how researchers study complex biological samples. His most cited paper (152 citations) investigates the molecular characterization of covalent complexes between tissue transglutaminase and gliadin peptides, shedding light on the pathogenesis of celiac disease and the enzyme's dual role as both an autoantibody target and a modifier of gluten peptides. This work has had a lasting impact on understanding autoimmune mechanisms. With over 30,000 total citations and an h-index exceeding 80, Roepstorff's contributions have shaped modern proteomics. He has also been recognized with numerous awards, including the prestigious European Mass Spectrometry Award, and has mentored a generation of scientists, making him a central figure in the field.