Nina Queisser

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About

Dr. Nina Queisser is a leading toxicologist whose research focuses on advancing genotoxicity testing through high-content, flow cytometry-based methodologies. Her major contribution is the development and validation of a multiplexed in vitro assay that simultaneously measures DNA damage, p53 activation, γH2AX induction, and mitotic alterations in a single, high-throughput platform. This work, detailed in her highly cited 2017 paper (74 citations), represents a significant leap beyond traditional genotoxicity screens by providing mechanistic insights alongside hazard identification. By incorporating internal counting beads for absolute nuclei quantification, her assay enhances reproducibility and throughput, addressing a critical need in regulatory toxicology. Dr. Queisser’s research has been instrumental in driving the adoption of integrated, multi-parametric approaches for chemical safety assessment, reducing reliance on animal testing. Her contributions are widely recognized in the field, with her work serving as a cornerstone for modern in vitro genotoxicity evaluation. Through her innovative assay design, she has empowered researchers to more accurately predict human genotoxic risk, making her a pivotal figure in the evolution of 21st-century toxicology.