Andreas Sutter

Papers

Total Citations

H-Index

About

Andreas Sutter is a distinguished toxicologist whose research focuses on advancing genotoxicity testing through innovative in vitro methodologies. His key contributions center on developing high-content screening assays that improve the detection of DNA damage and cellular stress responses. Sutter is best known for his seminal 2017 paper, "Interlaboratory evaluation of a multiplexed high information content in vitro genotoxicity assay," which has garnered 74 citations. This work introduced a groundbreaking flow cytometric approach that simultaneously analyzes multiple biomarkers—including p53, γH2AX, and phospho-histone H3—from detergent-liberated nuclei. By incorporating internal standards and enabling multiparametric assessment, Sutter's assay significantly enhances the sensitivity and specificity of genotoxicity screening while reducing false positives. His methodology represents a major advancement over traditional single-endpoint tests, offering a more comprehensive and efficient tool for evaluating chemical safety. Sutter's research has been instrumental in driving the adoption of integrated testing strategies in regulatory toxicology, demonstrating how mechanistic biomarkers can transform hazard identification. His work continues to influence both academic research and industrial safety assessments, making him a key figure in modern genetic toxicology.