Maxim Sokolov
Papers
1
Total Citations
34
H-Index
1
About
Maxim Sokolov is a leading vision researcher whose work illuminates the molecular machinery essential for photoreceptor health and survival. His primary research focuses on protein folding and trafficking in the retina, particularly the role of the chaperonin containing TCP-1 (CCT/TRiC) complex. In his seminal 2010 paper, which has garnered 34 citations, Sokolov demonstrated that disrupting CCT function severely compromises protein networks critical for rod outer segment morphogenesis—the light-sensing compartment of photoreceptor cells. This work revealed that CCT assists in folding approximately 10% of newly translated cytosolic proteins in eukaryotes, including key retinal proteins. His findings have profound implications for understanding retinal degenerative diseases, where protein misfolding and trafficking defects lead to cell death and vision loss. By connecting fundamental chaperone biology to photoreceptor survival, Sokolov has provided a framework for investigating therapeutic targets in inherited blindness. His research bridges molecular cell biology and ophthalmology, offering insights into how protein homeostasis sustains the delicate architecture of the vertebrate retina.
Research Focus
Key Achievements
Top Papers
- 1