Mark J. Edwards

National Hospital for Neurology and Neurosurgery, St George's, University of London

Papers

Total Citations

189

H-Index

About

Mark J. Edwards is a leading clinical neuroscientist whose research bridges the boundaries between movement disorders, motor control, and the neurobiology of agency. His most-cited work, “Loss of sensory attenuation in patients with functional (psychogenic) movement disorders” (160 citations), fundamentally advanced our understanding of how the brain’s sense of self-agency breaks down in these conditions, revealing that patients genuinely experience their abnormal movements as involuntary—a finding with profound diagnostic and therapeutic implications. Edwards has also made key contributions to dystonia research, including studies on DYT1 dystonia showing that high motor variability impairs visuomotor adaptation (20 citations), and work on DYT11 myoclonus-dystonia that delineates cerebellar mechanisms in saccadic adaptation (9 citations). His research integrates rigorous kinematic analysis with cognitive neuroscience, offering mechanistic insights into both organic and functional movement disorders. Edwards’ work has shaped how clinicians and scientists conceptualize volition, motor learning, and the pathophysiology of complex movement disorders, making him a pivotal figure in modern neurology.