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About

Laurent Berthe is a leading expert in laser–tissue interaction and laser lithotripsy, with a career spanning both biomedical and materials processing applications. His seminal work on the Holmium:YAG laser fundamentally redefined the concept of “ablation effect” in soft tissue, showing that the widely cited penetration depth of 0.4 mm does not correspond to actual incision depth—a critical distinction for clinical practice. This insight, published in his most-cited paper (53 citations), has reshaped how surgeons understand laser-tissue dynamics. Berthe’s comparative studies of the Ho:YAG and Thulium fiber lasers (50 citations) have provided essential benchmarks for ablation, coagulation, and carbonization in non-perfused tissue models, guiding the selection of laser systems for urological and surgical applications. He has also optimized non-contact lithotripsy techniques, improving stone ablation efficiency by controlling fiber-to-stone working distance. Earlier in his career, Berthe explored the intersection of lasers and thermal spray technology, demonstrating the synergistic potential of these high-energy processes for advanced coating applications. His ongoing work includes robotic-assisted standardized ablation rate comparisons across multiple laser platforms, further cementing his role as a key figure in precision laser surgery and materials engineering.