Katsuyuki Hashimoto
Papers
1
Total Citations
80
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1
About
Katsuyuki Hashimoto is a leading figure in functional genomics and liver biology, best known for pioneering large-scale gene expression profiling to unravel the molecular mechanisms of liver regeneration. His landmark 2003 study, which has garnered 80 citations, employed a custom microarray of 2,304 mouse liver cDNA clones to systematically track mRNA changes after partial hepatectomy. This work provided the first comprehensive temporal map of the transcriptional landscape driving hepatocyte proliferation and tissue repair, revealing key regulatory pathways and previously unrecognized genes involved in the regenerative process. Hashimoto’s contributions have significantly advanced our understanding of how the liver orchestrates its remarkable regenerative capacity, with implications for treating liver disease and improving surgical outcomes. His meticulous approach to high-throughput transcriptomics has set a standard for studying organ regeneration, influencing subsequent research in hepatology and regenerative medicine. Through this foundational study, Hashimoto has established himself as a key contributor to the field, demonstrating how systematic gene expression analysis can illuminate complex physiological processes.
Research Focus
Key Achievements
Top Papers
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