Jonathan Joseph Lowrey
Papers
1
Total Citations
22
H-Index
1
About
Dr. Jonathan Joseph Lowrey is a pioneering researcher in bioengineering and high-throughput biomedical assay technologies, with a primary focus on developing advanced three-dimensional (3D) scaffold-based platforms for toxicity evaluation. His most-cited work, "A ready-to-use, versatile, multiplex-able three-dimensional scaffold-based immunoassay chip for high throughput hepatotoxicity evaluation" (2015, 22 citations), represents a significant contribution to the field of hepatotoxicity screening. In this study, Dr. Lowrey ingeniously addressed a critical limitation of hydrogel-based 3D substrates—their high water content, which can dilute samples and impede mass transfer—by engineering a multiplex-able immunoassay chip that enhances signal detection and throughput. This innovation enables more accurate and efficient evaluation of drug-induced liver toxicity, a major challenge in pharmaceutical development. By integrating hydrogel scaffolds with miniaturized detection systems, his work bridges the gap between biomimetic 3D environments and practical, scalable diagnostic tools. Dr. Lowrey’s research not only advances the mechanistic understanding of cell-material interactions but also offers a ready-to-use platform for preclinical safety assessment, demonstrating his commitment to translating fundamental bioengineering principles into real-world biomedical applications. His contributions continue to inspire researchers seeking to improve the reliability and efficiency of high-throughput toxicity screening.
Research Focus
Key Achievements
Top Papers
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