Jianhong Zhou
Papers
2
Total Citations
42
H-Index
2
About
Jianhong Zhou is a molecular biologist whose work has advanced high-throughput methods for mapping protein-protein interactions—a cornerstone of post-genomic biology. Zhou’s key research focuses on developing innovative yeast two-hybrid (Y2H) screening platforms that overcome traditional limitations in accuracy, speed, and automation. In their most cited work, “A yEGFP‐based reporter system for high‐throughput yeast two‐hybrid assay by flow cytometry” (2008, 25 citations), Zhou engineered a fluorescent reporter system that enables rapid, quantitative detection of protein interactions using flow cytometry, dramatically increasing throughput while reducing cost. Building on this, Zhou’s 2009 study, “A surface display yeast two-hybrid screening system for high-throughput protein interactome mapping” (17 citations), introduced a surface-display approach that further streamlined the screening process, allowing for direct, real-time analysis of interaction libraries. These contributions have made high-throughput interactome mapping more accessible and reliable, providing tools that are widely adopted in systems biology and drug discovery. Zhou’s work stands out for its practical impact—enabling researchers to move from laborious, low-yield assays to automated, scalable pipelines that accelerate the discovery of functional protein networks.
Research Focus
Key Achievements
Top Papers
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