Claire K. Sanders
Papers
2
Total Citations
42
H-Index
2
About
Claire K. Sanders has made significant contributions to the field of high-throughput proteomics, with a particular focus on developing innovative tools for mapping protein-protein interactions. Her research centers on advancing the yeast two-hybrid (Y2H) assay, a cornerstone technique for studying interactomes in the postgenomic era. Sanders’s most notable work includes the development of a yEGFP-based reporter system for high-throughput Y2H assays using flow cytometry, which dramatically improves the speed, accuracy, and automation of interaction screening. This method, published in 2008, has garnered 25 citations and addresses critical limitations in traditional Y2H approaches. Building on this, she introduced a surface display Y2H screening system in 2009, further enhancing the efficiency of large-scale protein interactome mapping. Her contributions have enabled more cost-effective and scalable analysis of complex biological networks, making her a key figure in the advancement of functional genomics. Sanders’s work continues to empower researchers in systems biology and drug discovery, providing robust tools for unraveling the molecular basis of cellular processes.
Research Focus
Key Achievements
Top Papers
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