Jessica Yadav
Papers
1
Total Citations
45
H-Index
1
About
Jessica Yadav is a leading researcher in cancer glycobiology, with a focus on developing novel glycan-based biomarkers for early detection of pancreatic cancer. Her work addresses a critical gap in clinical oncology: the limitations of the CA19-9 assay, which relies on the sialyl-Lewis A (sLeA) glycan and fails to detect approximately 25% of pancreatic cancers. In her highly cited 2015 study (45 citations), Yadav and her team hypothesized that sLeA-low tumors secrete alternative glycans, leading to the discovery that plasma sialyl-Lewis X (sLeX) is significantly elevated in these otherwise missed cases. This pioneering "glycan motif profiling" approach has opened new avenues for more inclusive diagnostic strategies. Her contributions are vital for improving early detection rates of one of the deadliest cancers. With a growing citation impact, Yadav’s work is increasingly recognized as foundational in the shift from single-biomarker assays to comprehensive glycan panels, offering hope for more accurate and life-saving diagnostics.
Research Focus
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Top Papers
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