Galen Hostetter
Papers
1
Total Citations
45
H-Index
1
About
Dr. Galen Hostetter is a leading investigator in cancer glycobiology, with a primary focus on the role of glycan motifs in pancreatic cancer diagnostics. His most-cited work, a 2015 study on "Glycan Motif Profiling," directly addresses a critical limitation of the current gold-standard biomarker, CA19-9, which is based on the sialyl-Lewis A (sLeA) glycan and fails to detect approximately 25% of pancreatic cancers. Hostetter’s key contribution was the hypothesis that these sLeA-negative tumors instead secrete related glycans, such as sialyl-Lewis X, which could serve as alternative biomarkers. By profiling plasma glycans, his research provided a foundational framework for developing a more comprehensive, multi-glycan diagnostic panel. This work, which has garnered 45 citations, is pivotal for moving beyond single-marker assays toward a broader, more accurate detection strategy. Dr. Hostetter’s research is essential for students and researchers interested in the intersection of glycobiology and clinical oncology, offering a clear path toward improving early detection for one of the deadliest cancers.
Research Focus
Key Achievements
Top Papers
- 1