Douglas J. Hartman

Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa, Presbyterian Hospital

Papers

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About

Douglas J. Hartman is a pathologist and researcher whose work bridges molecular glycobiology and digital pathology. His key research areas include pancreatic cancer biomarker discovery, glycan-based diagnostics, and the application of telepathology in surgical settings. Hartman’s most notable contribution is his investigation of glycan motif profiling, where he demonstrated that plasma sialyl-Lewis X elevations occur in pancreatic cancers that are negative for the standard sialyl-Lewis A (CA19-9) biomarker. This finding addresses a critical gap, as CA19-9 is not elevated in approximately 25% of pancreatic cancers, limiting early diagnosis. His 2015 study, cited 45 times, has been influential in expanding the glycan biomarker landscape for pancreatic cancer. Additionally, Hartman has advanced the field of telepathology, authoring a 2018 review (19 citations) on its use for intraoperative consultations, highlighting its growing role in improving access to subspecialist expertise. His work is particularly valuable for students and researchers interested in translational pathology, cancer diagnostics, and the integration of digital tools into clinical practice.